Since molecular biology was first established, in the 1930s, the complexity of various biological systems have been explored in order to better understand these systems. As years went by, and our understanding of these systems increased, the information that fell under the, large and ever-growing, umbrella of “molecular biology” became more specific and eventually subdivided by the particular sub-field being studied. Some of these sub-fields include: genetics, proteomics, and cytology. Many of these sub-fields have become extremely popular and very well studied since molecular biology was first established.
Genome Project and Molecular Biology
In the more recent past, there has been an influx of quantitative research within molecular biology. This groundbreaking research has completed the connection between two popular sub-fields of molecular biology: computer science through use of bioinformatics and computational biology. This was most notably seen with the success of the Human Genome Project (HGP). The Human Genome Project allowed for over three billion nucleotide base pairs of euchromatic genome to be sequenced and presented as a reference. This was an important milestone of molecular biology which allowed the human genome to go from the analog world of biology into the digital world. This was a giant step, within the field of molecular biology, which caused a domino effect that resulted in thousands of human genomes to be sequenced with increasingly lower cost.
On 2rd June 2016, the Genome Project-Write (GP-write) announced a continuation of genomics research through multiple molecular biology tools. These multiple molecular biology tools included gene synthesis and genome editing technologies. These technologies are utilized to synthesize and test large portions of many genomes stemming from microbes, plants and even animals. GP-write’s commitment to furthering our understanding and effectiveness of these technologies has the possibility to improve research and development of the topics of life sciences, new bio-based therapies, and nutrition.
New era of molecular biology
Even as these recent accomplishments in molecular biology unfold, a new problem seems to be stemming from them. The problem that has come about comes in the form of designing and even artificially synthesizing new life.
A recent study has proven the ability to accomplish a complete chromosomal transplantation from one cell to another. After the transplant has been successfully conducted, the chromosome can then be activated to conduct various genetic activity. We can then utilize specific enzymes, digestive proteins and other substances within these cells. This combination will result in the cell’s loss of original features and a totally new species.
Due to the crisis of resource shortage critical to human sustainability partnered with the ever-increasing human population, there is a need for us to seek effective approaches for sustainable living. The furthering of our knowledge on biological systems through these technologies would have many positive effects on successfully creating a sustainable habitat. These positive effects would come as a result of better understanding of the physiology of cells, developing new molecular medicines, as well as generating sustainable energy sources, such as biofuels. All of these will contribute to a more successful living environment through the use of molecular biology.
One molecular biology technology, gene synthesis, has slowly become better understood over the past ten years and has drastically increased our capability of editing and synthesizing genes of interest. Synthesizing DNA artificially is very difficult and increases in difficulty when attempting to synthesize long genetic sequences. This is because the longer the sequence being generated is, the higher the possibility of generating errors. Therefore, a new method is required to successfully conduct gene synthesis and correct for all mistakes generated when the sequence was being synthesized.
As one of the leading companies in the field of synthetic biology, Synbio Technologies has unique proprietary GPS platform on the basis of genotype, phenotype and synotype. We can provide excellent molecular biology services including: plasmid DNA preparation, PCR cloning and subcloning, site-directed mutagenesis and vector construction. We have the ability to generate sequences that are de novo, meaning that the genetic sequence is not preexisting within any organism in biology. We also have the ability to generate sequences up to and including 200kb in length in addition to complex gene products and structures. Synbio Technologies prides itself in our ability to use these molecular biology technologies to better suite our customer’s needs when conducting various types of research.
Molecular Biology Related Services