Synbio Technologies is one of the leading DNA synthesis companies in the United States. We have developed the most comprehensive platforms of oligo synthesis, gene synthesis (fragment and clonal genes) and next generation high-throughput gene synthesis to meet our customers’ needs in quality, speed and budget. Typically, we synthesize over 3 million base pairs of gene sequences each month for a wide range of applications including antibody discovery, genetically engineered vaccine, molecular breeding, biofuel and many more.
According to the DNA or amino acid sequences you provided, our scientists will design oligos, template assembling, and cloning – sequencing – selection procedures within 30 minutes, using our automated system that guarantees efficient and error-free synthesis. To provide our customers with the highest quality product, Sanger sequencing will be conducted to verify the sequence accuracy. With our professional research team and effective systems in place, we provide our customers a one-stop shop that satisfy all their DNA synthesis needs.
 Standard ordering process to submit your request |  Recommended for orders containing more than 10 sequences |
Gene Synthesis Advantages
- Proprietary NGTM Codon Optimization Technology :
- FREE codon optimization, enables a significant increase in protein expression.
- Proprietary NGTM Codon Optimization Technology :
- Experienced Project Management Team:
- Provides professional and timely support throughout your entire project, from project design to project delivery.
- Experienced Project Management Team:
- Leading Syno® DNA Synthesis Platform:
- Complete platform with the entire Syno®1.0-3.0 technologies to meet the customer needs in flux, delivery cycle, pricing, synthesis difficulty and other different dimensions.
- Leading Syno® DNA Synthesis Platform:
- Syno® Assembly Technology：
- Capable of generating genetic sequences up to 150Kb.
- Syno® Assembly Technology：
- Guarantee 100% Sequence Accuracy:
- For all genes delivered by Synbio Technologies.
- Guarantee 100% Sequence Accuracy:
- Intellectual Property Protection:
- All our customers’ intellectual project related rights are fully respected and protected.
Standard Gene Synthesis Process
Gene Synthesis Services
| Syno® 2.0 Gene Synthesis 100% sequence accuracy, effectively deliver complex sequences including repetitive, strong hairpin, high GC content sequences | Syno® 3.0 Gene Synthesis Next generation DNA synthesis platform, high throughput and cost effective, gene synthesis starts at $0.09/bp, 100% sequence accuracy |
| NGTM Codon Optimization Patented codon optimization technology, increase of protein expression level in most host cells | Vector Construction shRNA, TALEN, CRISPR-Cas9 construction and validation |
| Small Genome Synthesis & Assembly Synthesis and Assembly Services on Gene Cluster and Small Genome, guarantee 100% accuracy on all of your delivered DNA orders | Pathway Synthesis & Assembly Proprietary metabolic pathway design platform, Syno® Assembly technology ensures long gene synthesis up to 200 kbp |
Gene Synthesis Service Specifications:
| Gene Length | Order Size | Codon Optimization | Price | Turnaround Time (business days) |
| < 1.5 kb | <100 kbp | Free (optional) | Starts at $0.19/bp Quote | 7-10 |
| 100-200 kbp | Free (optional) | Starts at $0.12/bp Quote | 20-35 | |
| 200-500 kbp | Free (optional) | Starts at $0.10/bp Quote | Quote | |
| >500 kbp | Free (optional) | Starts at $0.09/bp Quote | Quote | |
| 1.5-4 kb | <100 kbp | Free (optional) | Quote | 10-15 |
| ≥ 100 kbp | Free (optional) | Quote | Quote | |
| 4-6 kb | <100 kbp | Free (optional) | Quote | 20-25 |
| ≥ 100 kbp | Free (optional) | Quote | Quote | |
| 6-9 kb | <100 kbp | Free (optional) | Quote | 25-30 |
| ≥ 100 kbp | Free (optional) | Quote | Quote | |
| > 9 kb | <100 kbp | Free (optional) | Quote | Quote |
| ≥ 100 kbp | Free (optional) | Quote | Quote |
Note: The turnaround time and price apply to the non-complex sequences. Please contact service@synbio-tech.com to quote for the complex sequences.
Vector Information:
| Vector type | Antibiotic resistance | Multiple clone sites |
| Puc57-Amp | Ampicillin | Yes |
| Puc57-Kan | Kanamycin | Yes |
Delivery form:
Synbio Technologies’ standard package including:
- 4 µg of lyophilized plasmid DNA
- Sequencing chromatogram
- Certificate of analysis (COA)
Gene Synthesis Wiki
Related Services:
Professional cloning protocol.
Ability to clone any requested genetic sequence into any site of any vector.
Including: base deletion, insertion, site-directed mutagenesis and arbitrary editing.
High quality plasmids from research grade to transfection grade.
Guaranteed 3 mg protein of 85% purity with our Syno®Guaranteed Protein Package in E. coli expression system
Gene Synthesis Applications
- Humanized Antibody Library
- Protein Directed Evolution
- Genetic Engineering Vaccine
- Digital Information Storage
How to order gene synthesis services
 Online Inquiry |  service@synbio-tech.com |  +1 732-230-3003 |  +1 609 228 5911 |
Submit gene/protein sequence: Gene synthesis online inquiry.